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Multiple options are under consideration to treat the Covid-19 problem.
Research is ongoing to provide more extensive proof.
What follows are references to reports provided for educational
and informative purposes.
This is not medical advice nor promotional for commerce nor
intended for any deceptive purpose.
OZONE
Ozone in the air disinfects most pathogens including viruses
directly in the air and on surfaces.
For room air treatment, research is needed to determine,
what concentration is best to stop transmission of corona viruses,
while not irritating the lungs of people in the vicinity.
Ozone in ductwork is usually not a problem.
The spike proteins sticking out from every coronavirus are absolutely
necessary for attachment to the ACE2 receptors of respiratory cells.
These spike proteins contain multiple residues of the amino acids
L-cysteine and L-tryptophan.
"Important role for the transmembrane domain of severe acute
respiratory syndrome coronavirus spike protein during entry."
by Broer, et al. J Virol. 2006 Feb;80(3):1302-10
Reference Abstract
It is well known in chemistry that L-cysteine with its thiol group and
L-tryptophan with its double bonds are rapidly destroyed by ozone.
Ozone treatment of the blood has been used for many years
to stimulate the immune system, mostly outside the United States.
"Ozone and oxidation therapies as a solution to the emerging crisis
in infectious disease management: a review of current knowledge and experience."
by Rowen, Med Gas Res. 2019 Oct-Dec;9(4):232-237
Reference Abstract
"A Plausible "Penny" Costing Effective Treatment for Corona Virus - Ozone Therapy."
by Rowen & Robins, J Infect Dis Epidemiol 2020, 6:113
Reference Article
Reference Article
A Novel Approach to Treating COVID-19 Using Nutritional and Oxidative Therapies, by Brownstein,Rowen,et al:
Reference Article
Reference Same Article
HYDROGEN PEROXIDE
Doctor Frank Schallenberger long ago discovered a simple
method of defeating most respiratory infections.
He uses nebulized weak solutions of hydrogen peroxide.
"This At-Home Treatment Can Knock Out Any Virus Including the Coronavirus."
by Frank Shallenberger, MD, Second Opinion, March 9, 2020
Reference Article
Thomas E. Levy, MD, JD recently wrote an ebook, which provides
even more detail on the use of nebulized dilute hydrogen peroxide.
"Rapid Virus Recovery"
Get Free Ebook
Here is an article by Dr Levy regarding nebulizing hydrogen peroxide:
Reference Article
Doctor Mercola describes the aerosol hydrogen peroxide treatment for covid:
Reference Article
Doctor Mercola Interviews Doctor McCullough about nebulized povidone-iodine
and Doctor Brownstein about nebulized hydrogen peroxide.
Reference blogs with videos
Reference Brownstein Transcript
BLEACH
Bleach, also known as sodium hypochlorite (NaClO) solution, can be applied
to surfaces to rapidly disinfect viruses and other pathogens.
Rinse afterwards please, and do not take internally.
CHLORINE DIOXIDE
Chlorine dioxide (ClO2) is an effective and rapid acting disinfectant.
It is far less toxic than hypochlorite and has been found useful to sanitize
water and food. If suitably diluted and taken in low doses, it is surprizingly
well tolerated orally. It has been used extensively to kill malarial parasites
in vivo. Doctor Andreas Kalcker has recently adapted this to the treatment
of Covid-19 with amazing success in over 100 test cases per his research.
Some have recovered from advanced respiratory distress syndrome in just a few days.
Reference Website
Reference Article
Reference Video
ULTRA VIOLET
Ultraviolet light to surfaces as from the sun or lamps disinfects.
UV treatment of the blood to stimulate immunity has also been
used for many years, mostly outside the United States.
ZINC NUTRITION
Zinc is traditionally provided as an important nutrient,
which activates many enzymes in the body.
It is especially crucial to support optimal
immune function and to support wound healing.
"Zinc." by C Couinaud, J Chir (Paris). 1984 Oct;121(10):611-21
Reference Abstract
"Zinc deficiency in human subjects." by Prasad, Prog Clin Biol Res. 1983;129:1-33
Reference Abstract
For a thorough review of zinc nutrition and metabolism see:
"Zinc Fact Sheet for Health Professionals"
Reference Article
It is often quoted that the elderly are more susceptible to coronavirus
and that they develope more severe illness, more often require ventilation,
and have higher death rates from acute respiratory distress syndrome.
Zinc status was evaluated in 99 consecutive elderly patients.
67% of the group had plasma zinc levels in the DEFICIENT RANGE.
"Zinc levels of hospitalized elderly." by Paterson, et al.
J Am Diet Assoc. 1985 Feb;85(2):186-91
Reference Abstract
ZINC ANTIVIRAL
Trace Element Zinc, a Nature's Gift to Fight Unprecedented Global Pandemic COVID-19:
Reference Abstract
Reference Article
COVID-19: Poor outcomes in patients with zinc deficiency:
Reference Abstract
Reference Article
Low zinc levels at clinical admission associates with poor outcomes in COVID-19:
Reference Abstract
Reference Article As Text
Reference Article As PDF
ZINC IONOPHORES
Zinc in suitable models also functions as an antibiotic against most RNA viruses.
It powerfully inhibits RNA-dependent-RNA-polymerase (RdRp).
"The flavivirus polymerase as a target for drug discovery."
by Malet, et al. Antiviral Res. 2008 Oct;80(1):23-35
Reference Abstract
This video explains the mechanism behind anti-RdRp therapy,
using zinc and chloroquine. It is nicely illustrated by Medmastery.
Reference Video
Chloroquine Enables Zinc To Move Into Cells Where It Inhibits Coronavirus, explains Edgy Edge.
Reference Video
Zinc together with an ionophore (zinc moblizer) halts replication of the SARS coronavirus.
"Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro
and zinc ionophores block the replication of these viruses in cell culture."
by Velthuis, et al. PLoS Pathog. 2010 Nov 4;6(11):e1001176
Reference Abstract
See Doctor Vladimir Zelenko's protocol:
He modifies symptomatic corona cases to markedly reduced severity in only 5 days
using heavy zinc loading plus the ionophore hydroxychloroquine at normal dosages.
Reference Report
Zelenko's 5 day protocol:
zinc sulfate heptahydrate = ZnSO4.7H2O, 220 mg, 2x daily,
(each 220mg capsule delivers 50 mg of elemental zinc)
hydroxychloroquine sulfate = HCQS, 200 mg, 2x daily
azithromycin = Zithromax, 500 mg, 1x daily
Martin Scholz & Roland Derwand & Vladimir Zelenko
are preparing a manuscript to fully document the
results of this triple therapy.
"COVID-19 Outpatients – Early Risk-Stratified Treatment
with Zinc Plus Low Dose Hydroxychloroquine and Azithromycin:
A Retrospective Case Series Study"
Reference Abstract
Doctors Zelenko, Risch, and Fareed recently published an ebook thoroughly
discussing HCQ related protocols with reprints and references.
The title is "Medical Studies Support MDs Prescribing Hydroxychloroquine
for Early Stage COVID-19 and for Prophylaxis"
Reference Article
Watch Doctor Anthony Cardillo explain his positive experience:
Reference Video
LA doctor seeing success with hydroxychloroquine to treat COVID-19
Reference Report
Note that hydroxychloroquine sulfate must be given with zinc to be effective,
as HCQS only serves as an ionophore to enable zinc to enter infected cells.
See Doctor Oz interview Dr Cardillo:
Reference Video
Doctor Robin Armstrong treated residents at "Resort" nursing home,
in Texas City, using the same triple therapy (hydroxychloroquine,
zinc, and azithromycin). All but one survived. There were no
adverse reactions and no signs of cardiac problems per ECG testing.
Reference Article
Reference Video
See Laura Ingraham interviews Dr Armstrong:
Reference Video
"Researchers at NYU's Grossman School of Medicine found patients given the
antimalarial drug hydroxychloroquine along with zinc sulphate and the antibiotic
azithromycin were 44 percent less likely to die from the coronavirus."
Reference Report
Dr. Simone Gold, MD, JD has testified in public in favor of the combined
HCQ with Zinc treatment. She also has prepared a thorough review of this topic
complete with references. The title is "White Paper on Hydroxychloroquine".
Reference Article
Dr. James Torado has also testified in public in favor of the combined
HCQ with Zinc treatment. He also compiled interesting references of ongoing
research and experiences of clinicians using related protocols.
Reference Article
He further debunks criticisms against HCQ use in relation to alleged heart problems.
Reference Article
There is a new professional society of physicians favorable to HCQ related therapies.
It is appropriately called "America's Frontline Doctors".
Reference Website
For videos of their lectures see:
Reference Conference
This links to a listing of multiple studies world-wide using hydroxychloroquine
under various conditions. Most reports are favorable.
Reference Website
Hydroxychloroquine is at times in short supply. In some places HCQ is banned
by adversarial regulators. Therefore additional ionophores for zinc related
antiviral therapies need to be discovered right away.
My favorite two favorite candidates for this pending further research are:
L-carnosine, 500mg, 2x daily with zinc, 50mg, 2x daily taken together at the same time or
picolinate, 100mg, 2x daily with zinc, 50mg, 2x daily taken together at the same time.
Click here to read about hypothetical candidates.
QUERCETIN
Quercetin serves to benefit the Covid patient by several mechanisms.
It is antiinflammatory, antioxidant, and virus inhibiting.
Two New Studies Show Quercetin Improves COVID Outcomes
Reference Article
Quercetin Alternative for Covid, reviewed by Joseph Mecola,DO:
Reference Article
Anti-inflammatory potential of Quercetin in COVID-19 treatment.
by Boroujeni & Sani
Journal of Inflammation, 18(3), 28 January 2021
Reference Article
Reference Article as PDF
Quercetin and Vitamin C: An Experimental, Synergistic Therapy
for the Prevention and Treatment of SARS-CoV-2 Related Disease (COVID-19)
(Quercetin blocks viral processes at several points, while vitamin C supports its functions.)
by Biancatelli1, Berrill, Catravas, Marik
Reference Article
Potential Clinical Benefits of Quercetin in the Early Stage of COVID-19:
by Di Pierro, et al
Results of a Second, Pilot, Randomized, Controlled and Open-Label Clinical Trial
International Journal of General Medicine 2021:14 2807–2816
Reference Article as html
Reference Article as PDF
Quercetin Phytosome as a potential candidate for managing COVID-19
by Di Pierro, et al
Minerva Gastroenterology, 2021 June, 67(2):190-5
Reference Article as html
Reference Article as PDF
Quercetin-Phytosome Preparation Explained by Thorne:
Reference Article
VITAMIN C = ASCORBATE
Doctor Richard Cheng explains how vitamin C is powerful aid to coronavirus infection.
Here is a report of early successes in China.
"Early Large Dose Intravenous Vitamin C is the Treatment of Choice for 2019-nCov Pneumonia"
Reference Article
Preliminary experiences in China report marked improve
using high doses of intravenous vitamin C.
Reference Report
Dr Cheng explains the pathologic sequence of coronavirus in the lungs
and how this is mitigated by antioxidants such as vitamin C.
Reference Video Presentation
Dr Chegs's clinic and blogs:
Reference Blogs
VITAMIN D
Vitamin D is a powerful immune enhancing nutrient.
Doctor Renu Mahtani MD explains the nutrition and physiology of Vitamin D.
She explains how Vitamin D enhances resistance to infection generally
and resistance to CoViD-19 particularly.
Reference Video
Editorial: low population mortality from COVID-19 in countries south
of latitude 35 degrees North supports vitamin D as a factor determining severity
Reference Article
Reference Abstract
Vitamin D's Effect On Immune Function
"...the evidence of a link between vitamin D deficiency and adverse outcomes is
overwhelming and clearly points towards avoidance of vitamin D deficiency..."
Reference Article
Reference Abstract
Optimal Nutritional Status for a Well-Functioning Immune System
Is an Important Factor to Protect against Viral Infections
Nutrients 2020, 12, 1181
Reference Article
Reference Abstract
The role of vitamin D in the prevention of coronavirus disease 2019
infection and mortality. by Ilie, Stefanescu & Smith
Aging Clin Exp Res. 2020 May 6
"Vitamin D levels are severely low in the aging population especially
in Spain, Italy and Switzerland. This is also the most vulnerable group
of the population in relation to COVID-19."
Reference Article
Reference Abstract
Evidence that Vitamin D Supplementation Could Reduce Risk
of Influenza and COVID-19 Infections and Deaths.
"Evidence supporting the role of vitamin D in reducing risk of COVID-19
includes that the outbreak occurred in winter, a time when 25-hydroxyvitamin D
concentrations are lowest; that the number of cases in the Southern Hemisphere
near the end of summer are low; that vitamin D deficiency has been found to
contribute to acute respiratory distress syndrome; and that case-fatality rates
increase with age and with chronic disease comorbidity, both of which are
associated with lower 25(OH)D concentration."
Reference Article
Reference Abstract
IVERMECTIN
Look for more on this antiparasitic drug repurposed against coronavirus.
The FDA-approved Drug Ivermectin inhibits the replication of SARS-CoV-2 in vitro
Reference Article
Common Anti-Parasite Drug May Kill Coronavirus in Under 48 Hours, Say Researchers
Reference Report
Dr. Pierre Kory Senate Testimony On Early COVID-19 Treatments
Reference Video
There is a new organization of physicians using and promoting ivermectin
to both prevent and to treat coronavirus.
FLCCC official website
More medical references regarding efficacy of ivermectin:
References
L-LYSINE
Herpes viruses and coronaviruses are dependent upon a plentiful supply
of L-arginine. Since L-lysine blocks utilization of L-arginine,
supplemental L-lysine in conjunction with a low L-arginine diet reduces
the severity of these illnesses. L-lysine supplementation of 2 to 3 grams
per day has been shown clinically to mitigate coronavirus infection.
"Virologists Report Poor Man’s Amino Acid Cure For Covid-19
Would Abolish Need For Vaccines", by Bill Sardi
Reference Article
Lysine Therapy for SARS-CoV-2
by Christopher Kagan, Alexander Chaihorsky, Rony Tal, Bo Karlicki
Reference Article
Bo Karlicki from Dominican Republic shares his experiences and observations
treating coronavirus cases with L-lysine in an interview.
Reference Video
Lysine Supplements As Adjuvants To Treat COVID-19
Reference Article
"The origin of SARS-CoV-2 furin cleavage site remains a mystery"
[Note: this site contains L-arginine]
Reference Article
"The sequence at Spike S1/S2 site enables cleavage by furin and
phospho-regulation in SARS-CoV2 but not in SARS-CoV1 or MERS-CoV"
"P3 arginine in R-R-x-R motif is necessary for efficient cleavage
of S1/S2 site substrate constructs by furin."
Reference Article
BROMELAIN
This is an enzyme that digests and dissolves proteins. It naturally occurs
in pineapples. Fresh pineapple cannot be used in gelatin molds because this
enzyme will liquify the gelatin. Bromelain is sold with salt as a meat
tenderizer. It can be obtained from most health-food stores as 500mg taken
2x or 3x daily between meals with clear liquids to optimize absorption.
This has been used for many years to reduce inflammation, pain and swelling
in the body. Recent research has shown that it can dissolve spike proteins
the toxic agent of coronavirus. Hopefully this can work systemically to
inhibit inflammation, spike functions and coagulation in active covid cases.
Supportive literature is cited below:
"The Combination of Bromelain and Acetylcysteine (BromAc) Synergistically Inactivates SARS-CoV-2" by Akhter, et al
Reference Article
"Bromelain inhibits SARS-CoV-2 infection via targeting ACE-2, TMPRSS2, and spike protein." by Radhakrishnan, et al
Reference Article
"Bromelain Inhibits SARS-CoV-2 Infection in VeroE6 Cells." by Sagar, et al
Reference Article
"An Analysis Based on Molecular Docking and Molecular Dynamics Simulation
Study of Bromelain as Anti-SARS-CoV-2 Variants" by Tallei, et al
Reference Article
ANDROGEN BLOCKERS
These would be drugs such as spironolactone, dutasteride and finasteride.
Androgens such as testosterone, dihydrotestosterone and androstanedione
naturally occur in the body in both males and females. These have the
peculiar side-effect of inducing increased levels of transmembrane protease
serine (TMPRSS) on the surfaces of cells. Normally this is fine. However,
coronavirus uses TMPRSS to penetrate cells. To inhibit this problem during
an active covid infection androgen blockers have been found beneficial.
Also this androgen effect on TMPRSS implies that the following should
temporarily be stopped: supplemental testosterone, herbs that enhance
testosterone functions, and aromatase inhibitors.
"Targeting the viral-entry facilitators of SARS-CoV-2
as a therapeutic strategy in COVID-19." by Muralidar, et al
Reference Article
"TMPRSS11D and TMPRSS13 Activate the SARS-CoV-2 Spike Protein" by Kishimoto, et al
Reference Article
"Contributions of human ACE2 and TMPRSS2 in determining
host-pathogen interaction of COVID-19." by Senapati, et al
Reference Article
"COVID-19 and the male susceptibility: the role of ACE2, TMPRSS2
and the androgen receptor" by Mjaess, et al
Reference Article
"Early Antiandrogen Therapy With Dutasteride Reduces Viral Shedding,
Inflammatory Responses, and Time-to-Remission in Males With COVID-19:
A Randomized, Double-Blind, PlaceboControlled Interventional Trial
(EAT-DUTA AndroCoV Trial – Biochemical)" by Cadegiani, et al
Reference Article
"Spironolactone may provide protection from SARS-CoV-2:
Targeting androgens, angiotensin converting enzyme 2 (ACE2),
and renin-angiotensinaldosterone system (RAAS)." by Cadegiani, et al
Reference Article
FAMOTIDINE
Famotidine is a type 2 histamine receptor blocker. This reduces the production
of acid in the stomach. It is traditionally used therefore to treat:
hyperacidity, gastric ulcers, duodenal ulcers, esophagitis, and reflux disease.
Blocking histamine activity in the lungs is also helpful to reduce excessive
inflammation as occurs with covid pneumonia.
"Effect of famotidine on hospitalized patients with COVID-19:
A systematic review and meta-analysis"
Reference Article
"COVID-19: Famotidine, Histamine, Mast Cells, and Mechanisms"
Reference Article
"Famotidine use and quantitative symptom tracking for COVID-19"
Reference Article
"Impact of Famotidine Use on Clinical Outcomes of Hospitalized Patients With COVID-19"
Reference Article
MORE EXPERT INFORMATION
There is a growing number of scientists, researchers and clinicians
contributing to our knowledge about the covid pandemic and how best
to respond. The link below serves a video website with well prepared
interviews of these experts.
Reference Videos
For an ever expanding lists of well studied treatment options click the following:
America's Frontline Doctors, Treatment Options
Off Label Alternative Drug Treatments
For a directory of doctors treating covid and explanations of their therapies and more:
Doctors, Treatments, Exposes
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